ABSTRACT
Introduction: Coronavirus disease 2019 (COVID-19) affects children but mostly has mild course. There is meagre published data on the impact of COVID-19 illness in children with Severe Aplastic anemia (SAA). We describe our experience of managing COVID-19 in children with SAA. Method: Three children of SAA who developed SARS-CoV-2 infection are included in this study. Results: Patient 1 was post Immunosuppressive therapy (IST) for SAA and had an asymptomatic course and uneventful recovery. Patient 2 was several months post IST with no response and had an asymptomatic COVID-19 illness but had delayed viral clearance, however he succumbed to bacterial sepsis soon after. Patient 3 was awaiting IST and while he contracted severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) infection, he had symptomatic COVID-19 illness followed by bacterial and fungal sepsis to which he succumbed. Conclusion: COVID-19 in children with SAA can be mild to fatal course and virus may have delayed clearance. It can lead to delay in therapy of SAA. © 2022 Pediatric Hematology Oncology Chapter of Indian Academy of Pediatrics
ABSTRACT
Background: The impact of the severity of the COVID-19 on potential long-term consequences is currently not well documented. With a 6-minute walk test, we followed up on 30 patients who were COVID 19 survivors with varied CT-Severity scores. The aim was to correlate the CTSeverity score with 6 minute walk distance and percentage desaturation. Methods: Data of post COVID-19 patients who presented to our hospital from January to June 2021 were collected. Patients who had undergone a HRCT scan during their admission time were chosen and followed up with 6 minute walk test and data was analyzed. Results: In the 30 patients, whose data was analyzed, 19 were male and 11 were female. Of the 30 patients whose reports were analyzed, 15 (50%) had CT-Severity score between 6-14 (moderate). Only 10 (33.3%) patients had CT-Severity score more than 15 (severe) and of them only 3 had desaturation more than 10% on 6MWT. While only 3 patients had desaturation between 5-10%, majority of the patients (24/30) had less than 5% desaturation on 6MWT. More than half the patients (17/30;56.7%) walked more than 350 metres in 6 minutes, while 11 patients walked between 150-350 metres and only 2 patients walked less than 150 metres. Conclusion: In COVID-19 survivors, we conclude that CTSeverity has minimal effect on exercise tolerance.
ABSTRACT
The covid-19 outbreak has appeared to be a threat to mankind for all the countries, especially India. The first wave of this virus arrived in the country in 2020, and due to various control measures taken by the government, the situation was somewhat controllable. Unfortunately, the second wave has brought enormous trouble to the citizens, and even the measures couldn't possibly stop the mess. This study presents a comprehensive analysis of the second wave of corona virus spread in India, along with visualized information about vaccination undertaken by the citizens. The datasets over which the study has been performed are taken from 16 January 2021 to 2nd May 2021. © 2021 IEEE.